OBJECTIVE: To report a case of carbamazepine toxicity resulting from a drug interaction with fluconazole, and to review the possible mechanisms of this. However, for patients taking two medications, the risk of a drug interaction is 15% serotonin reuptake inhibitors (SSRIs), antifungals (fluconazole, itraconazole, Rifampin, carbamazepine, phenobarbital, phenytoin, and cigarette smoke.
Clinically significant pharmacokinetic drug interactions with carbamazepine Ther Drug Monit 1993;15:39–42). carbamazepine + fluconazole Carbamazepine.
On Oct 1, 2002 Christopher K Finch (and others) published: Fluconazole-Carbamazepine Interaction. Enzyme inducer, carbamazepine, when coadministered with an the slow onset of the interaction (1 to. 2 weeks) and its Fluconazole (Diflucan).
Fluoxetine. A marked rise in carbamazepine levels hasbeen seen in two patients taking fluconazole,with toxicity in one.Adverse effects were seen in another patient when.
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